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There was no experience up to now with the use of METROGEL-VAGINAL in Expecting people. Metronidazole crosses the placental barrier and enters the fetal circulation rapidly. No fetotoxicity or teratogenicity was noticed when metronidazole was administered orally to Expecting mice at six moments the advised human dose (based upon mg/m2); on the other hand, in just one little examine where by the drug was administered intraperitoneally, some intrauterine deaths have been noticed. The relationship of those results for the drug is unidentified.
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